Is Interstitial Cystitis an Autoimmune Disease?

What is an autoimmune disease?

An autoimmune disorder occurs when the body's immune system attacks and destroys healthy body tissue by mistake. Autoimmune disorder causes abnormally low activity or overactivity of the immune system. In cases of the immune system overactivity, the body attacks and damages its own tissues. Immune deficiency diseases decrease the body's ability to fight invaders, causing vulnerability to infections. In response to an unknown trigger, the immune system may begin producing antibodies that instead of fighting infections, attack the body's own tissues.

How many auto-immune diseases are there?

There are almost 100 autoimmune diseases.

What is the treatment for auto-immune diseases?

Treatment for autoimmune diseases generally focuses on reducing immune system activity.

Is Interstitial Cystitis an auto-immune disease?

Yes, Interstitial Cystitis is one of the auto-immune diseases.

Are all auto-immune diseases rare?

Many auto-immune disorders like Type 1 Diabetes, Ankylosing spondylitis, and Chagas diseases are common however diseases like adult Still's disease, interstitial cystitis, and achalasia are rare.

Are all auto-immune diseases chronic and progressive?

Some autoimmune diseases like auto-immune hepatitis, Lyme disease are chronic, some are progressive like MMN, MS while others like herpes gestationis are temporary.

Here is the list of auto-immune diseases includes:

·         Achalasia (rare)

·         Addison’s disease(rare)

·         Adult Still's disease(rare)

·         Agammaglobulinemia

·         Alopecia areata

·         Amyloidosis

·         Ankylosing spondylitis (common and hereditary)

·         Anti-GBM/Anti-TBM nephritis(rare)

·         Antiphospholipid syndrome

·         Autoimmune angioedema

·         Autoimmune dysautonomia

·         Autoimmune encephalomyelitis

·         Autoimmune hepatitis

·         Autoimmune inner ear disease (AIED) (rare)

·         Autoimmune myocarditis

·         Autoimmune oophoritis

·         Autoimmune orchitis

·         Autoimmune pancreatitis

·         Autoimmune retinopathy

·         Autoimmune urticaria

·         Axonal & neuronal neuropathy (AMAN)

·         Baló disease(rare)

·         Behcet’s disease

·         Benign mucosal pemphigoid(rare)

·         Bullous pemphigoid

·         Castleman disease (CD) (rare)

·         Celiac disease

·         Chagas disease (common)

·         Chronic inflammatory demyelinating polyneuropathy (CIDP)

·         Chronic recurrent multifocal osteomyelitis (CRMO) (rare) 1::1000000

·         Churg-Strauss Syndrome (CSS) or Eosinophilic Granulomatosis (EGPA)

·         Cicatricial pemphigoid(rare)

·         Cogan’s syndrome

·         Cold agglutinin disease

·         Congenital heart block(rare)

·         Coxsackie myocarditis

·         CREST syndrome

·         Crohn’s disease

·         Dermatitis herpetiformis

·         Dermatomyositis

·         Devic’s disease (neuromyelitis optica)

·         Discoid lupus

·         Dressler’s syndrome

·         Endometriosis

·         Eosinophilic esophagitis (EoE)

·         Eosinophilic fasciitis(rare)

·         Erythema nodosum

·         Essential mixed cryoglobulinemia

·         Evans syndrome(rare)

·         Fibromyalgia(not autoimmune but accompany other autoimmune diseases)

·         Fibrosing alveolitis

·         Giant cell arteritis (temporal arteritis)

·         Giant cell myocarditis(rare)

·         Glomerulonephritis

·         Goodpasture’s syndrome

·         Granulomatosis with Polyangiitis(rare)

·         Graves’ disease

·         Guillain-Barre syndrome(rare)

·         Hashimoto’s thyroiditis

·         Hemolytic anemia

·         Henoch-Schonlein purpura (HSP)

·         Herpes gestationis or pemphigoid gestationis (PG)

·         Hidradenitis Suppurativa (HS) (Acne Inversa)

·         Hypogammalglobulinemia

·         IgA Nephropathy

·         IgG4-related sclerosing disease

·         Immune thrombocytopenic purpura (ITP)

·         Inclusion body myositis (IBM)

·         Interstitial cystitis (IC)

·         Juvenile arthritis

·         Juvenile diabetes (Type 1 diabetes)

·         Juvenile myositis (JM)

·         Kawasaki disease

·         Lambert-Eaton syndrome

·         Leukocytoclastic vasculitis

·         Lichen planus

·         Lichen sclerosus

·         Ligneous conjunctivitis(rare)

·         Linear IgA disease (LAD)

·         Lupus

·         Lyme disease chronic

·         Meniere’s disease

·         Microscopic polyangiitis (MPA)

·         Mixed connective tissue disease (MCTD) (rare)

·         Mooren’s ulcer(rare)

·         Mucha-Habermann disease

·         Multifocal Motor Neuropathy (MMN) or MMNCB(rare)

·         Multiple sclerosis

·         Myasthenia gravis

·         Myositis

·         Narcolepsy

·         Neonatal Lupus

·         Neuromyelitis optica

·         Neutropenia

·         Ocular cicatricial pemphigoid(rare)

·         Optic neuritis

·         Palindromic rheumatism (PR)

·         PANDAS(rare)

·         Paraneoplastic cerebellar degeneration (PCD) (rare)

·         Paroxysmal nocturnal hemoglobinuria (PNH) (rare)

·         Parry Romberg syndrome(rare)

·         Pars planitis (peripheral uveitis)

·         Parsonage-Turner syndrome

·         Pemphigus

·         Peripheral neuropathy

·         Perivenous encephalomyelitis

·         Pernicious anemia (PA)

·         POEMS syndrome(rare)

·         Polyarteritis nodosa

·         Polyglandular syndromes type I, II, III

·         Polymyalgia rheumatica

·         Polymyositis(rare)

·         Postmyocardial infarction syndrome

·         Postpericardiotomy syndrome

·         Primary biliary cirrhosis

·         Primary sclerosing cholangitis

·         Progesterone dermatitis(rare)

·         Psoriasis

·         Psoriatic arthritis

·         Pure red cell aplasia (PRCA) (rare)

·         Pyoderma gangrenosum(rare)

·         Raynaud’s phenomenon

·         Reactive Arthritis

·         Reflex sympathetic dystrophy

·         Relapsing polychondritis(rare)

·         Restless legs syndrome (RLS)

·         Retroperitoneal fibrosis(rare)

·         Rheumatic fever

·         Rheumatoid arthritis

·         Sarcoidosis

·         Schmidt syndrome(rare)

·         Scleritis

·         Scleroderma

·         Sjögren’s syndrome

·         Sperm & testicular autoimmunity

·         Stiff person syndrome (SPS) (rare)

·         Subacute bacterial endocarditis (SBE)

·         Susac’s syndrome(rare)

·         Sympathetic ophthalmia (SO)

·         Takayasu’s arteritis

·         Temporal arteritis/Giant cell arteritis

·         Thrombocytopenic purpura (TTP)

·         Tolosa-Hunt syndrome (THS) (rare)

·         Transverse myelitis

·         Type 1 diabetes

·         Ulcerative colitis (UC)

·         Undifferentiated connective tissue disease (UCTD)

·         Uveitis

·         Vasculitis

·         Vitiligo

·         Vogt-Koyanagi-Harada Disease(rare)

List courtesy: https://www.aarda.org/diseaselist/